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|
Assays
|
Groups
|
S/Co ranges
|
|---|
|
< 1
|
1–2.5
|
2.5–4
|
> 4
|
|---|
|
Ortho ELISA
|
Viremia (n)
|
0
|
1
|
0
|
263
|
|
%
|
0.0
|
0.4
|
0.0
|
99.6
|
|
Consistent (n)
|
0
|
47
|
34
|
142
|
|
%
|
0.0
|
21.1
|
15.2
|
63.7
|
|
Discrepant (n)
|
80
|
73
|
26
|
16
|
|
%
|
41.0
|
37.4
|
13.3
|
8.2
|
|
Murex ELISA
|
Viremia (n)
|
0
|
22
|
29
|
213
|
|
%
|
0.0
|
8.3
|
11.0
|
80.7
|
|
Consistent (n)
|
0
|
29
|
21
|
173
|
|
%
|
0.0
|
13.0
|
9.4
|
77.6
|
|
Discrepant (n)
|
86
|
41
|
17
|
51
|
|
%
|
44.1
|
21.0
|
8.7
|
26.2
|
|
Architect CMIA
|
Viremia (n)
|
0
|
0
|
2
|
262
|
|
%
|
0.0
|
0.0
|
0.8
|
99.2
|
|
Consistent (n)
|
0
|
70
|
20
|
133
|
|
%
|
0.0
|
31.4
|
9.0
|
59.6
|
|
Discrepant (n)
|
29
|
92
|
47
|
27
|
|
%
|
14.9
|
47.2
|
24.1
|
13.8
|
|
Elecsys ECLIA
|
Viremia (n)
|
0
|
0
|
0
|
264
|
|
%
|
0.0
|
0.0
|
0.0
|
100.0
|
|
Consistent (n)
|
0
|
0
|
0
|
223
|
|
%
|
0.0
|
0.0
|
0.0
|
100.0
|
|
Discrepant (n)
|
152
|
2
|
3
|
38
|
|
%
|
77.9
|
1.0
|
1.5
|
19.5
|
- aIn each of the four assays, specimens were classified into three groups: (1) HCV RNA positive group (Viremia, n = 264); (2) HCV RNA negative, anti-HCV consistent group (Consistent, n = 223); (3) HCV RNA negative, anti-HCV discrepant group (Discrepant, n = 195). In each group, the specimens were further divided into four S/Co ranges with specific numbers and percentages. S/Co value < 1.0 was considered as anti-HCV negative while S/Co value > 4 was considered strongly anti-HCV positive
